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US Department of Defense
BLAST INJURY RESEARCH
COORDINATING OFFICE
Advancing Blast Injury Research to Protect and Heal Those Who Serve

Blast Injuries in Focus

Hearing/balance injuries

Blast-related Hearing and Balance Injuries

Hearing injuries impede communication, reduce situational awareness, hinder threat detection, and ultimately impair Service members' safety and mission effectiveness. Peripheral hearing loss, central auditory processing deficits, tinnitus, and vestibular impairment are among the primary clinical conditions associated with blast exposure. Even in relatively mild cases of blast-related auditory injury, initial symptoms of pain, tinnitus, hearing loss, dizziness, or disorientation can threaten individual and military unit effectiveness. Although these initial symptoms and deficits may dissipate over hours or days, blast overpressure can tear the eardrum, fracture delicate middle ear bones, and disrupt hearing by blocking the ear canal with blood, debris, or foreign bodies. If left untreated, some blast-related injuries may lead to permanent impairment. Read more...

Hemorrhage

Blast-related Hemorrhage

Hemorrhage is the leading cause of preventable death on the battlefield and is directly associated with many types of blast injuries, such as abdominal bleeding, internal organ perforation, and traumatic amputations. Approximately 25 percent of these combat casualties could be prevented with timely, effective hemorrhage control closer to the point of injury. Beyond acute blood loss, severe hemorrhage triggers systemic secondary complications including shock, systemic inflammation, coagulopathy, profound hypotension, and tissue hypoxia, which worsen clinical outcomes for casualties with concurrent trauma like TBI. Advanced resuscitative treatment and immediate hemorrhage control within the first hour after injury (the "golden hour") remain the most critical strategies for saving combat casualties.

Extremity

Blast-related Extremity Injuries

Extremity injuries accounted for most total battle injuries sustained in modern conflicts. In contested operational environments characterized by artillery, improvised explosive devices (IEDs), and weaponized drone payloads, blast-related extremity injuries continue to produce high rates of infection, extensive soft-tissue trauma, volumetric muscle loss, nerve damage, and complex scarring. Many of these wounds necessitate one or more amputations. The clinical management of Service members with amputations or complex limb trauma requires a comprehensive, coordinated, multidisciplinary healthcare team across the entire continuum of care, employing advanced practices in surgical reconstruction, modern prosthetic and orthotic technology, and intensive rehabilitation management.

Brain

Blast-related Traumatic Brain Injuries

Blast-related traumatic brain injury (TBI) is commonly caused by secondary and tertiary blast mechanisms, such as penetrating fragment wounds and blunt—impact head trauma. The extent to which brain injury can be caused by the primary mechanism of blast overpressure alone—without secondary or tertiary physical impacts to the head—remains an area of continuing clinical investigation. Recent defense research also focuses heavily on the cumulative, systemic effects of repetitive low-level blast overpressure (BOP) encountered during weapons training, breaching, and exposure to loitering munitions.

Ocular/Vision

Blast-related Ocular and Vision Injuries

Combat-related eye injuries have increased substantially due to the proliferation of explosive weaponry, including improvised explosive devices (IEDs) and modern unmanned aerial systems (UAVs) deploying loitering and dropped munitions. In contrast to peacetime ocular trauma, combat eye injuries are frequently bilateral and commonly present alongside concurrent head, neck, or polytrauma. Multiple operational and anatomical factors account for this disproportionately high incidence relative to the small surface area of the eye: the operational necessity of preferential visual exposure in combat environments, limited facial armor and ocular protection, the structural vulnerability of the eye to high-velocity micro-fragments, and the evolving nature of explosive threats and asymmetric munitions.

Last modified: 20-Oct-2026